Lilemong tsa bo-1990, litsebi tsa bongaka tsa Switzerland li fumane hore li-platelet li ka hlahisa palo e kholo ea lintlha tsa kholo ka mekhahlelo e phahameng, e ka lokisang maqeba a lisele kapele le ka katleho.Kamora moo, PRP e ile ea sebelisoa ho opereishene e fapaneng ea kahare le kantle, opereishene ea polasetiki, phetisetso ea letlalo, jj.
Re kile ra tsebisa kopo ea PRP (Platelets Rich Plasma) ho kenya moriri ho thusa ho hlaphoheloa ha leqeba le ho hōla ha moriri;Ha e le hantle, teko e latelang ea ho leka ke ho eketsa ho koaheloa ha moriri oa mantlha ka ho kenya PRP.Ha re boneng hore na ke liphello life tse tla finyelloa ka ho kenya plasma ea autologous e matlafalitsoeng le lintlha tse fapaneng tsa kholo ho bakuli ba banna ba nang le alopecia, eo hape e leng phekolo eo re ka lebellang ho e sebelisa ho loantša tahlehelo ea moriri.
Pele le nakong ea ts'ebetso eohle ea ho kenya moriri, bakuli ba phekoloang ka PRP le ba sa kenngoa ka PRP ba ka etsa hore moriri o hōle ka potlako.Ka nako e ts'oanang, mongoli o boetse a etsa tlhahiso ea phuputso ho netefatsa hore na plasma e ruileng ea platelet e na le phello e tšoanang ho ntlafatsa moriri o motle.Ke leqeba la mofuta ofe le lokelang ho sebelisoa le hore na ke ntho e kae ea ho hōla e lokelang ho kenngoa ka ho toba hore e atlehe?Na PRP e ka fetola ho fokotseha ha moriri butle-butle ka alopecia ea androgenic, kapa na e ka susumetsa ka katleho ho hōla ha moriri ho ntlafatsa alopecia ea androgenic kapa mafu a mang a tahlehelo ea moriri?
Nakong ea teko ena e nyenyane ea likhoeli tse robeli, PRP e ile ea kenngoa letlalong la lihlooho tsa androgenic alopecia le alopecia.Ha e bapisoa le sehlopha sa taolo, ka sebele e ka fetola ho fokotseha butle-butle ha moriri;Ho phaella moo, ha e kenngoa ho bakuli ba nang le lefatla le chitja, ho hōla ha moriri o mocha ho ka bonoa khoeli hamorao, 'me phello e ka nka nako e fetang likhoeli tse robeli.
Selelekela
Ka 2004, ha e mong oa bafuputsi a tšoara leqeba la pere ka PRP, leqeba le ile la fola ka mor'a khoeli e le 'ngoe' me moriri oa hōla, 'me joale PRP e sebelisoa ho opereishene ea ho kenya moriri;Bafuputsi ba ile ba boela ba leka ho kenya PRP holim'a letlalo la bakuli ba bang pele ho fetisoa ha moriri, 'me ba fumana hore moriri oa bakuli o ne o bonahala o le motenya (1).Bafuputsi ba lumela hore revascularization le phello ea litaba tse phahameng tsa kholo e ka susumetsa kholo ea lisele tsa moriri letlalong la sebaka se sa sebetseng.Mali a sebetsoa ka ho khetheha.Li-platelet li arotsoe ho liprotheine tse ling tsa plasma 'me li na le li-platelet tse ngata.Ho finyella tekanyo ea phello ea phekolo, ho tloha ho 1 microliter (0.000001 litha e le nngwe) e nang le 150000-450000 platelet ho 1 microliter (0.000001 litha e le nngwe) e nang le 1000000 platelets (2).
Platelet α e na le mefuta e supileng ea lintlha tsa kholo ho li-granules, ho kenyelletsa le epithelial growth factor, fibroblast growth factor, thrombogen growth factor le transforming growth factor α, Interleukin-1, le vascular endothelial growth factor (VEGF).Ho phaella moo, li-peptide tsa antimicrobial, catecholamines, serotonin, Osteonectin, von Willebrand factor, proaccelenn le lintho tse ling li kenngoa.Likaroloana tse teteaneng li na le mefuta e fetang 100 ea lintlha tsa kholo, tse ka sebetsang maqebeng.Ntle le lintlha tsa kholo, platelet sparse plasma (PPP) e ka thōko e na le limolek'hule tse tharo tsa adhesion cell (CAM), Fibrin, fibronectin, le vitronectin, protheine e nang le mesebetsi e mengata e behang mohaho o ka sehloohong le makala ho laola kholo ea lisele, ho khomarela, ho ata, karohano le nchafatso.
Takakura, et al.o boletse hore lets'oao la PDCF (platelet derived growth factor) le amana le tšebelisano ea li-follicles tsa moriri oa epidermal le lisele tsa dermal stromal, 'me lia hlokahala bakeng sa ho theha masela a moriri (3).Ka 2001, Yano et al.e bontšitse hore VFLGF haholo-holo e laola potoloho ea ho hōla ha moriri, e fana ka bopaki bo tobileng ba hore ho eketseha ha moriri oa methapo ea moriri ho ka khothalletsa kholo ea moriri le ho eketsa boholo ba moriri le boholo ba moriri (4).
PS: Platelet derived growth factor, PDCF.Ntho ea pele ea kholo e amohetsoeng ke US FDA ho phekola kotsi e sa foleng ea letlalo ke ntlha ea pele ea kholo e lokollotsoeng ka ts'usumetso ka mor'a kotsi ea letlalo.
PS: Vascular endothelial growth factor, VEGF.Ke e 'ngoe ea lintlha tsa bohlokoa tsa taolo tse laolang ho ata ha lisele tsa endothelial, angiogenesis, vasculogenesis le vascular permeability.
Haeba re lumela hore ha melapo ea moriri e fokotsehile hoo re ke keng ra bona ho hōla ha moriri ka leihlo le hlobotseng, ho ntse ho e-na le monyetla oa hore moriri o mela moriri (5).Ho phaella moo, haeba moriri oa moriri o motle o tšoana le oa moriri o mahoashe, ho na le lisele tsa stem tse lekaneng ka har'a epidermis le bulge (6), ho ka khoneha ho etsa hore moriri o be mosesaane le ho feta lefatleng la banna.
Nako ea poso: Dec-20-2022